Abstract OBJECTIVE: To investigate the effects of a near-physiological peripheral glucagon-like peptide-1 (GLP-1) infusion, during and after a breakfast of fixed energy content, on resting energy expenditure, substrate oxidation and metabolism and the desire to eat specific types of food in humans
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Dr Timothy OConnor
The study identifies certain liver endothelial cells as a key node, but it remains to be clarified how much of the benefit derives from a strictly local action and how much depends on systemic changes associated with the treatment
You think the problem is a lot bigger than it is
