Reconstitution should be performed under sterile conditions using appropriate aseptic technique
Menezo Y, Khatchadourian C, Gharib A, et al
One case study indicates that activated charcoal may help treat diarrhea, but higher quality studies are necessary (25)
Patients should be reviewed 812 weeks after commencing treatment to assess: Symptomatic improvement, particularly resolution of fatigue and neurological symptoms Haematological response (normalisation of haemoglobin and mean cell volume) Reticulocyte count typically rises within one week, indicating bone marrow response Repeat serum B12 testing is generally not useful after starting parenteral therapy, as levels remain elevated for months
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