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Semaglutide physiologically mimics the function of endogenous GLP-1 hormone, promoting insulin secretion and suppressing glucagon secretion

This fatty acyl-CoA immediately enters the beta-oxidation pathway, where it is systematically broken down to produce acetyl-CoA

While semaglutide may cause side effects, the risk of a reaction due to sulfa ingredients is not present because it does not contain any sulfonamides

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Keep it Clean: Ensure the skin is cleaned with an alcohol swab and allowed to dry completely before the injection

While acknowledging the importance of T2D in fibrosis progression, the MAESTRO-NASH trial design imposed specific criteria for participants with diabetes, who comprised ~70% of the study population