It is that metformin has been evaluated within a far more stringent system, and obtaining it requires a prescription, whereas berberine is subject to far less scrutiny and is available to order online with no medical oversight or third-party quality control checking the purity of the ingredients
To put that into perspective, if you weigh 200 pounds, thats a loss of 30 pounds
Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects
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