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The peptide's ability to cross the blood-brain barrier and activate MC4R on oxytocin neurons positions it as a potential pharmacological tool for enhancing behavioral therapies targeting social deficits in psychiatric disorders

Because they bypass thyroid function to address hunger and satiety, GLP-1 compounds can be effective for weight loss even when thyroid levels are properly managed with medication

To address any uncertainty surrounding whether patients had collected and then taken their prescribed medication, which is a major limitation of prescription data, we conducted a more stringent sensitivity analysis in subgroups of patients who had at least two prescriptions for their GLP-1 RA in the baseline period, suggesting that they had used their first prescription

The decision framework articulated herein provides a structured approach to this problem, replacing narrative optimism with transparent criteria

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