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At maintenance, you may lose 0.5-1.5 pounds weekly, though some patients experience plateaus lasting weeks before additional losses resume

10.1016/j.forsciint.2024.112246 354 PainoldA.MrklS.KashoferK.HalwachsB.DalknerN.BengesserS.et al

Morning works best for researchers with mild side effects who want daytime appetite suppression and a potential glycemic advantage

Because B12 in its organic form comes from animal sources like fish, meat, eggs and dairy, vegans, vegetarians and people with nutrient deficient diets need B12 supplementation to meet minimal health requirements

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In this case, you would benefit from using the XL first thing in the morning or using the IR twice per day (but skipping the final dose)