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doi: 10.1038/s41467-018-03941-2 50 LuceyMPickfordPBitsiSMinnionJUngewissJSchoenebergKet al

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They started to propose that the formation of oxygen free radicals induced tissues and cell damage [2]

And I'll just give you the top line results which the study was positive at two years, which was the follow up, the authors found that discontinuing anticoagulation led to lower rates of adverse events compared to continuing regulation