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GLP-1, a hormone primarily secreted from the ileum in response to nutrient intake, exerts multiple metabolic effects including appetite suppression, delayed gastric emptying, enhanced insulin secretion, and inhibition of glucagon release [4]
The authors reported statistically significant mean reductions in body weight from baseline across the retatrutide groups relative to placebo, with the magnitude differing by dose level
Bahrainwala has seen patients who lost substantial weight on GLP-1 therapy and needed their blood pressure medications reduced or stopped altogether
Within two weeks, he started to feel full after eating small-to-medium portions of food
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