Common causes include: Pernicious anemia, an autoimmune disorder hindering Vitamin B12 absorption Gastrointestinal surgeries, like gastrectomy, impact Vitamin B12 uptake Long-term use of certain medications, such as metformin or proton pump inhibitors Diets lacking in Vitamin B12, often seen in vegans and vegetarians For those without a deficiency, Vitamin B12 injections are not typically recommended, as their body can naturally regulate and excrete excess amounts of the vitamin
PlexusDx offers MIC-B12 through its Longevity Protocols, with current details on the MIC-B12 product page
10.1016/j.bbamcr.2022.119263 46 PatschanD.HildebrandtA.RinneburgerJ.WesselsJ
Useful specifically for early satiety and bloating
Interpretation of Cobalamin Status and Diseases Cobalamin status can be affected by various diseases either directly (e.g., by affecting its absorption and/or metabolism) or indirectly (e.g., by interfering with its intake)
ncRNAs also influence tumor Gln metabolism by modulating various signaling pathways ( Table 1 )
