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The UK Summary of Product Characteristics (SmPC) for Mounjaro advises caution in patients at risk of dehydration and recommends appropriate fluid management, especially during dose titration

Nausea is a side effect that tends to occur early on in treatment

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Managing stress through breathing exercises or mindfulness reduces visceral hypersensitivity that can amplify nausea perception

Weight from fluid retention may resolve quickly, while actual fat gain or the distinctive "moon face" and fat redistribution, particularly in the abdomen, takes longer to reverse