In ICH, the initial injury by the rupture of vessels and the compression of the expanding hematoma is mostly followed by secondary damage, which involves hemoglobin cytotoxicity, microglial activation, and inflammatory cell infiltration in the perihematomal region (Yang et al., 2020)
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The same is true for GLP-1 drugs , such as Ozempic and Wegovy , which are now widely prescribed to treat type 2 diabetes and obesity
Immunoblot assays Cell lysates from HCC-1806, PC3 WT and PC3 GGT1 + cells were obtained by placing PBS-washed cell plates on ice and scraping with RIPA buffer (Thermo Scientific, 89900) containing Halt Protease and Phosphatase Inhibitor cocktail (Thermo Scientific, 1861280)
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