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Particularly useful in screening for aggressive cancers that are not typically diagnosed until late stage, like ovarian and pancreatic cancer

We found that the glycolytic flux into the TCA cycle was reduced in Gclc fl/fl Mb1-Cre + FoB compared to Gclc fl/fl FoB, as indicated by increased M3-lactate and reduced M2-citrate (Supplementary Fig

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They are also involved in the inception and pathogenesis of several chronic diseases including neurodegenerative disorders, diabetes, aging processes, arthritis, cardiovascular impairment, chronic inflammation, and hepatic disorders 33

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