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Understanding how dosing works and what to expect at higher concentrations helps patients make informed decisions about their treatment journey
Hormonal activation of glycogen synthase (GYS) involves both allosteric interaction with glucose-6-phosphate (G6P) and dephosphorylation promoted by kinase inhibition including GSK3, protein kinase A, and adenosine monophosphate-activated protein kinase (AMPK) and phosphatase activation (primarily protein phosphatase 1 [PP1]) (Fig
This condition is typically painless but can cause sudden, irreversible vision loss
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This occurs in about a quarter of patients presenting with status epilepticus
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