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of the CY 2023 OPPS/ASC proposed rule (87 FR 44715 through 44716)), and certain diagnostic tests within the medicine range that are covered ancillary services, the established policy is to set the payment rate at the lower of the PFS unadjusted nonfacility PE RVU-based amount or the amount calculated using the ASC standard ratesetting methodology

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Peptide-based approaches can target both types of tolerance

Semaglutide and tirzepatide are GLP-1 receptor agonists (tirzepatide also targeting GIP), mimicking gut hormones that regulate satiety and blood sugar a well-established pathway with extensive human data

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