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L., Bancalari, E

Mitochondrial iron overload-mediated inhibition of Nrf2-HO-1/GPX4 assisted ALI-induced nephrotoxicity

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Reproduction 154 , R123R131 (2017)

The amino acid sequence is in the public domain and there is no composition-of-matter patent worth pursuing, so no commercial sponsor will fund the hundreds of millions a Phase IIIII development programme costs for a compound it cannot exclusively monetise

In addition to short stature, the developmental delay and cognitive disability are typical features which tend to worsen over time, leading to an autism-like phenotype, including self-mutilation behaviors, skin picking, learning problems, irritability, and compulsive behaviors [26]