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CC chemokines contain four consecutive conserved cysteine residues, whereas CXL chemokines display four cysteines, with two tandem cysteine residues separated by a single amino acid

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Size is classified into three categories according to a modification of the criteria of the Collaborative Ocular Melanoma Study (COMS): small, medium and large melanomas

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In vitro experiments revealed that DEC significantly reduced intracellular ROS levels and enhanced Nrf2-mediated antioxidant defenses in melanocytes, while suppressing AGE-RAGE signaling

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