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Safety Considerations, Medical Screening, and Who Should Transition Transition is generally appropriate for patients with stable renal function, no personal or family history of medullary thyroid carcinoma, and no contraindications to GLP-1 or GIP agonism

Amyloid- peptide is the main component of Alzheimer's plaques that can cause neuronal cell death, and it can cause oxidative damage to RBCs

The data from Cover et al

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Tilting the redox balance towards oxidative stress in nucleated cells, i.e., by increasing the ROS levels, normally leads to cell death (apoptosis) or to an acceleration in ageing [111]