High levels of fumarate accumulate and act as oncometabolites, which often result in dysregulation of cellular functions in SDH- or FH-deficient cells [1]
Mansson JE, Chlebowski RT, Stefanick ML, et al
Luce siempre lista para la cmara: una piel luminosa y de tono uniforme se ve hermosa en las fotografas desde cualquier ngulo y con cualquier iluminacin
Czabak-Garbacz, R., et al
It has been observed to preserve mitochondrial integrity, reduce neuronal apoptosis, and improve cerebral blood flow
A history of exposure to a hepatotoxicant and the presence of multiple nodules of regeneration that maintain a lobular but usually distorted architecture makes diagnosis more convincing