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Some patients reach therapeutic benefit at 1mg weekly, while others require titration to 2.4mg or compounded formulations for adequate appetite suppressiondifferences rooted in physiological variation rather than compliance

Since semaglutide delays stomach emptying, keeping it in your system raises the risk of aspiration while under anesthesia

J Lipid Res 2012;53:2256-2265

Post hoc analyses suggest potential sex- and age-dependent effects, warranting confirmation in larger, adequately powered studies

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