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Among those who stopped taking a GLP-1, cost was the most frequently cited reason, surpassing experiencing side effects or achieving a desired weight

Additional documented interactions include the FAK-paxillin pathway, fibroblast activity, and dopaminergic, serotonergic, and GABAergic neurotransmitter systems, though these represent a more preliminary evidence base

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They increase satiety and reduce appetite and calorie intake

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