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Background GLP-1R agonists protect the blood-brain barrier (BBB): These drugs help maintain the integrity of the BBB by preventing tight junction degradation, which can reduce the risk of neuroinflammation and cognitive decline

Moreover, a significant accumulation of CD8 + T cells has been observed in the adipose tissue of high-fat diet-fed mice, a phenomenon that mirrors the elevated CD8 + T cell levels reported in obese individuals [113,114,115]

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Moreover, 6 subjects (15.4%) in the EGCG group and 4 subjects (10.5%) in the placebo group took antihypertensive medications

It can help signal fullness, slow digestion, and reduce cravings, which may help patients consume fewer calories throughout the day

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