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Historical Background and Scientific Context Scientific interest in metabolic regulatory compounds has expanded significantly with advances in molecular biology and biochemical research

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The 2015 regional fact sheet of IDF estimates the prevalence to be 10.7%, 8.5%, and 3.2% in the Middle East and North Africa (MENA), South East Asia (SEA), and African regions, respectively.[1] This increasing burden of the disease may contribute to increased rate of complications, reduction of quality of life, and premature mortality

doi: 10.1001/jamaophthalmol.2022.0052 [DOI] [PMC free article] [PubMed] [Google Scholar] 30.Centers for Disease Control and Prevention