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3.2 Lipid accumulation Lipid accumulation is a common feature in the tubular cells of patients with DKD ( Lipotoxicity in renal TECs is associated with inflammation, oxidative stress, mitochondrial dysfunction and cell death ( Hypercholesterolemia also results in lipid deposition in kidney tissue, further compromising oxygen delivery through diffusion ( 3.3 Hypoxia Renal hypoxia has been observed in animal models of diabetes ( The enormous oxygen consumption in the kidneys is largely due to tubular reabsorption

Champe, PC and Harvey, RA

However, supplementation might be beneficial for those with chronic illnesses, high oxidative stress, or conditions like liver disease

But the evidence we have so far points to their promise in studying bone health and preventing age related bone loss

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