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Estudios de 24 semanas o ms en monoterapia106,111 muestran que los distintos ISLGT2 son eficaces en reduccin de HbA1c, con una aparente superioridad de CANA (Tabla 8)

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This dual activation leads to improved insulin secretion in response to elevated blood glucose levels, while also reducing glucagon levels, thereby optimizing blood sugar control

This leads to enhanced muscle protein synthesis, improved fat metabolism, and better tissue repairmaking it ideal for both bulking and body recomposition

A randomized controlled trial of dapagliflozin plus once-weekly exenatide versus placebo in individuals with obesity and without diabetes: metabolic effects and markers associated with bodyweight loss