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Additionally, Lys17, upon further modification (e.g., K26 in Semaglutide), is expected to enhance the binding affinity of SR18 to serum albumin (Supplementary Figure S2), improving its in vivo pharmacological functions

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Previous studies have demonstrated that electroconvulsive shock can activate microglia, upregulate proinflammatory cytokines, and enhance OS responses [38]

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