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[80] Nicotine affects neurological, neuromuscular, cardiovascular, respiratory, immunological and gastrointestinal systems

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While it can be reasonably argued that Holmes himself would have preferred something considerably stronger to tussle with, my own inner Sybarite simply enjoys this blend on its own merits, and I suspect I will blow through this tin in short order

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It is a serious health hazard that affects non smokers of all ages