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FBCM is currently considered to be the most common cause of vitamin B12 deficiency, caused by impairment in the release of the vitamin from food, commonly because of conditions such as gastritis, achlorhydria, gastrectomy, use of antacids, or proton pump inhibitors (PPIs), gastric atrophy in the elderly, and Helicobacter pylori infection (63, 74)

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While compounded medications are not FDA-approved as branded drugs, they meet the same pharmaceutical-grade standards

Longer term: steady state and fuller effects With consistent weekly dosing, weight loss often continues gradually over many months before reaching a plateau

Thats where treatments like PT-141 (bremelanotide) have started gaining attention