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Neuron 92 , 187201 (2016)

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CagriSema vs Tirzepatide (REDEFINE 4): strong weight loss, but an important endpoint miss Novo Nordisk has announced headline results from the open-label phase 3 REDEFINE 4 trial comparing CagriSema (cagrilintide + semaglutide) vs tirzepatide 15 mg in obesity

Tirzepatide activates GLP-1 and GIP receptors, reducing appetite and caloric intake while improving insulin sensitivity

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