Interactions with other diabetes medications: To avoid potential interactions, close monitoring is advised when using tirzepatide alongside other diabetes medications, such as sulfonylureas, SGLT-2 inhibitors, metformin, or insulin
Lab work helps providers assess metabolic health and ensure treatment is appropriate
Doctors often base their recommendation on the patient's overall health, co-existing conditions, and potential side effect management
Tirzepatide carries a similar gastrointestinal side effect profile to semaglutide, though some patients report milder nausea
Contraindications: Zepbound should not be used for certain conditions, including a personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or a serious allergic reaction to tirzepatide or any of the ingredients in Zepbound
Most available studies only include people exposed to GLP-1 agonists very early in pregnancy (typically no later than the first trimester)
