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The phagocytosis of microorganism, death cells, PtdSer binding or FcR promotes the recruitment of the Rubicon-containing PI3K complex (Beclin 1, VPS34, UVRAG) to the phagosome, where it ensures localized PI3P synthesis

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D., Kolling, J., Mescka, C

Interestingly, we see marginal release of cytochrome c following 5FU and a transient dip in MOMP, but no enhanced difference in sensitivity to BH3-mimetics or increase in ATF4 expression or predicted activity in RNA-seq analysis (data not shown)