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14 Inhibitors of these enzymes, such as gemfibrozil, clopidogrel, ketoconazole and trimethoprim may increase the risk of pioglitazone dose-related side effects

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Serum and whole blood clinical safety markers As can be seen in Table 4, there was a significant main effect for Group that existed for urea nitrogen and absolute basophils ( p 0.05) suggesting none of the clinical chemistry variables were significantly changed over the course of the 8 weeks for either group, and that neither group differed from the other