Archives of Biochemistry and Biophysics, 239 (2), 538548
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In most diseases, ROS appear to have a direct connection with inflammaging and cell senescence, and oxidative stress and inflammaging increase the aging-related phenotype, and induce and aggravate the inflammatory response, creating a chronic state of systemic inflammation (290297)
Diet is not a definitive cure, but it plays an important role in controlling and reducing the severity of the disease
de Bengy, A.-F., Decorps, J., Martin, L
In line with the importance of TXNRD1 in the regulation of ferroptosis and apoptosis in AML cells, auranofin, a TXNRD1 inhibitor, impaired cell viability in AML subtypes dependent on TXRND1 for their protection against ferroptosis [53]