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With the rapid rise in use of medications like semaglutide and tirzepatide, its reasonable to ask not only what they do for weight and blood sugar, but also how they affect mood, emotions, and the brain

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Though they have historically been used to help patients manage their type 2 diabetes, Semaglutide GLP-1 injections have recently become approved for use as part of medical weight loss treatments

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Vasodilation is achieved by activating endothelial nitric oxide synthase (eNOS) and increasing nitric oxide (NO) production via the cAMP/PKA, AMPK, and PI 3 K/Akt signaling pathways [17]