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It isnt even close to being evidence of efficacy or safety

Allele frequencies for genetic polymorphism are such that ~1 in 300 Caucasians is homozygous for a defective allele or alleles for the trait of very low activity, ~11% of people are heterozygous and have intermediate activity

While significant studies affirm its hepatic safety, additional long-term research is essential to comprehensively assess its effects on liver health, particularly in individuals with predisposing risk factors

(1) Cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in patients with heart failure

, Tanikawa et al