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Diabetes and bone health

368 Since GLP-1R is expressed in thyroid C cells and GLP-1 directly stimulates the secretion of calcitonin, which is a potent inhibitor of bone resorption in osteoclasts, GLP-1 may contribute to the nutrient-mediated reduction in bone resorption

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Mean MACE-related costs (for a first event) are estimated to be about $20,000 per patient

About 42 drug manufacturers, including smaller ones, are expected to launch products under more than 50 brand names this year, said Sheetal Sapale, a researcher at market data firm Pharmarack