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The methodological quality of the included studies, as assessed through the Jadad and NewcastleOttawa scales, varied from moderate to high, while the GRADE assessment indicated moderate certainty of evidence for serum vitamin B12 increase and low certainty for homocysteine reduction

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While there was an improvement in cobalamin levels in both groups not all dogs achieved B12 sufficiency

Machan S, El Shabrawi-Caelen L, Nikolay E, Kerl H, Requena L, Cerroni L

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