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It produces worse side effects, more discontinuations, and often slower progress because severe GI symptoms prevent adequate nutrition and hydration

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De Vos M, Mielants H, Cuvelier C et al (1996) Long-term evolution of gut inflammation in patients with spondyloarthropathy

Liquid sublingual formulations are typically less stable than troches and should always be refrigerated once opened

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2.7.2 Relative Quantitative Analysis Whole target relative quantitative analysis is a canonical method based on UPLC/HRMS metabolomics, which obtains the original mass spectrometry data through the preparation of mixed solutions of an internal isotope standard, correction solutions for the standard curve, and sample solutions