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Notably, the Drosophila blastoderm and the vertebrate neural tube are typical examples of gradient-mediated cell fate decision spatially ( in vivo methods are not yet feasible or practical

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Thus, astrocytes represent an excellent model to investigate GSH production due to their higher GSH levels and enzymatic efficiency

Indeed, the downregulation of only one of these proteins reduces PCCs metabolic flexibility with the accumulation of FA-intermediate metabolites in the mitochondria

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