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Each one exploits a different feature of the U.S

(1.4) Prurigo Nodularis for the treatment of adult patients with prurigo nodularis (PN)

Response: We decline to require a signature within the MRF file, given that the MRF required formats, JSON and CSV, do not permit the inclusion of electronic signature solutions

500 The study revealed that patients receiving a single intravenous dose of ustekinumab (130 mg or 6 mg/kg) followed by a maintenance dose of 90 mg subcutaneously every 8 weeks experienced a significant reduction in symptoms such as rectal bleeding and no significant adverse events