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For a heavy man with low-normal testosterone and no urgent fertility timeline, losing weight first is often the right move before reaching for hormones

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The experimental drug, retatrutide, helped people lose, on average, about 24% of their body weight, the equivalent of about 58 pounds, in a mid-stage clinical trial, the company said Monday from the American Diabetes Association's annual meeting in San Diego

The researchers found that the drugs tended to cause weight loss for about nine months, but then weight loss plateaued

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