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Digestive symptoms such as persistent diarrhea, abdominal pain, rectal bleeding, unexplained weight loss, fever, severe bloating, food intolerance patterns, or nighttime bowel movements deserve medical attention

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Unless stated otherwise, measurements were performed in 0.1 M PBS (pH 7.0)

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[68] performed a multicenter study of 101 PEH repair with anterior gastropexy without fundoplication, showing an acceptable recurrence rate of 16.8% at 12-month follow-up and avoiding complications of mesh positioning and anti-reflux procedures