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Whether the research focus is metabolic, body composition, or exploratory, the core principles remain: Start low: 0.5 to 1 mg is a safe starting dose

Studies in animal models have investigated its effects on conditions like drug-induced catalepsy, serotonin syndrome, and recovery from traumatic brain injury (TBI)

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Another issue of concern that must be comprehensively explored in future trials is the association between tesofensine and increased frequency of agitation and mood changes