10.1056/NEJMoa2032183 90 YangJ.RenJ.SongJ.LiuF.WuC.WangX.et al (2013)
470,478,482,483,484 GLP-1RAs in the digestive system Treatment with GLP-1RAs can alleviate insulin signaling by reducing the phosphorylation of Akt protein (Decreased Akt-P) and activating Protein Kinase C- (PKC-)
Patients should not think these medications are a simple quick fix, emphasizes an OBGYN on Sermo
Additionally, reduced water consumption decreases saliva production, which normally protects throat tissue from irritation
This amplifies the many challenges associated with GLP-1s, like gastrointestinal side effects, nutrient inadequacies, muscle and bone loss, low long-term adherence, weight regain, and high costs
Body-Composition Effects of Semaglutide (STEP 1 Study) Wilding JPH et al