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Between 10 and 15 percent of people taking GLP-1s are considered nonresponders, meaning that they lose less than 5 percent of their starting weight on the maximum tolerated dose

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GLP-1 receptors exist in the dorsal vagal complex of the brainstem

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In January 2025, the ITC issued a notice stating it was not going to review the summary determination order but sought further comments on public interest and remedy

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