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GLP-1 medications are unlikely to eliminate characteristic lipedema fat distribution

Cosmos Study - Collaboration March 3, 2026 Dual-Team Study Team A:Kersten Bartelt, RNKendall F Moseley, MDJoe Deckert, PhD Team B:Dave Little, MDEmily Higgs Key Findings Among adults with type 2 diabetes, osteoporosis risk was lower for patients prescribed a GLP-1 than for patients who were not prescribed a GLP-1, when compared to a baseline of stable-weight patients who were not prescribed a GLP-1

A phase IIa, double-blind, placebo-controlled study, enrolled patients with biopsy proven NASH with fibrosis stage 1-3, BMI 25, and hepatic fat fraction 10% on MRI-PDFF

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This includes tirzepatides (Mounjaro and Zepbound) and liraglutide (Saxenda)

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