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In addition, IL-4 / mice had decreased production of tumor necrosis factor , CXCL1 and interleukin-1 in the liver, but not in a remote site such as the lungs

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Pese a la vida media corta en plasma, los efectos biolgicos posteriores persisten en el tejido durante mucho ms tiempo, lo que es coherente con una cascada de sealizacin en lugar de una actividad dosis-respuesta directa

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