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Large outcome trials demonstrate that GLP-1RAs reduce major adverse cardiovascular events (MACE), even in non-diabetic individuals with obesity

Diabetes and bone health

The challenge is not identifying demand, it is understanding what language consumers respond to, what outcomes they expect, and what makes them hesitate

The food-service sector, already struggling with higher labour costs, may find it even harder to sustain traffic, especially among younger consumers who represent the core of GLP-1 adoption

For example, Oeseberg showed that dipeptidyl-peptidase 4 (DPP-4) inhibition significantly reduced vascular senescence in a diabetic rat model

Metoclopramide should be used for a maximum of 5 days, whilst domperidone is restricted to short-term use at the lowest effective dose due to potential side effects and contraindications