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Others benefit from switching to pure semaglutide formulations if their genetic profile or previous trial history suggests GLP-1 dominance is their strength

Need for Medical Supervision Given the potential risks, ongoing medical supervision is critical

Tirzepatide works by mimicking the hormones GLP-1 and GIP, which regulate hunger and fullness

When those GLP-1 receptors are activated more strongly or more consistently than your body is used to, gastrointestinal effects, such as nausea, bloating or diarrhoea, can occur

Peptides work gradually, so results build over time rather than hitting all at once

A second direction of the interrelationship between psoriasis and obesity indicates that patients with psoriasis have elevated levels of inflammatory cytokines, particularly TNF-, which can lead to metabolic abnormalities, including insulin resistance, and may consequently lead to the development of obesity (211)