For example, people with liver or kidney disease or who are overweight or obese are known to have a carnitine deficiency or lower levels than otherwise healthy people
however, the bioavailability of ALCAR is thought to be higher than that of L-carnitine
A 2013 meta-analysis of 17 randomized, placebo-controlled studies in a total of 1,625 participants with heart failure found that oral L-carnitine (1.5-6 g/day for seven days to three years) significantly improved several measures of cardiac functional capacity (including exercise tolerance and markers of the left ventricle function), yet had no impact on all-cause mortality (56)
An intervention study compared the effect of L-carnitine supplementation (2 g/day for 12 weeks) on plasma and skeletal muscle carnitine concentrations and physical performance between 16 vegetarian and 8 omnivorous male participants (131)
People on weight management programs
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