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A novel and potent imidazo[4,5-c] quinolone derivative (NVP-BEZ235), which has entered phase I/II clinical trials in patients with advanced solid tumors, has a potential role in cisplatin-sensitive cancers by dual targeting of the PI3-K (phosphatidylinositol 3-kinase) and mTOR (mammalian target of rapamycin) kinases for NPC treatment

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To view a copy of this licence, visit About this article Cite this article Yang, X., Yin, W., Xu, M

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